Center for Drug Evaluation and Research Application Number: 22-554 Microbiology Review(s) Microbiology Review Division of Special Pathogen and Transplant Products

CENTER FOR DRUG EVALUATION AND RESEARCH APPLICATION NUMBER: 21-306 PHARMACOLOGY REVIEW(S) 1 REVIEW AND EVALUATION OF PHARMACOLOGY AND TOXICOLOGY DATA Division of Anesthetic, Critical Care, and Addiction Drug Products (HFD-170) Supplemental Review

Epidemiology of mecA-Methicillin Resistant Staphylococcus aureus in Iran: A Systematic Review and Meta-analysis

Objective(s)Staphylococcus aureus is a prevalent pathogen worldwide. Methicillin resistant S. aureus (MRSA), which is usually multi-resistant in hospitals, has been a daunting challenge for clinicians for more than half a century. The aim of this systematic review and meta-analysis is to determine the relative frequency (RF) of MRSA in different regions of Iran.Materials and MethodsSearch terms...

Pharmaceutical Advances and Proteomics Researches

Proteomics enables understanding the composition, structure, function and interactions of the entire protein complement of a cell, a tissue, or an organism under exactly defined conditions. Some factors such as stress or drug effects will change the protein pattern and cause the present or absence of a protein or gradual variation in abundances. Changes in the proteome provide a snapshot of the...

Pharmaceutical Advances and Proteomics Researches

Proteomics enables understanding the composition, structure, function and interactions of the entire protein complement of a cell, a tissue, or an organism under exactly defined conditions. Some factors such as stress or drug effects will change the protein pattern and cause the present or absence of a protein or gradual variation in abundances. Changes in the proteome provide a snapshot of the...

Clostridium Perfringens Toxin Types Associated with Meat: Review in Iran

Food poisoning due to Clostridium perfringens (C. perfringens) is a major food health problem, particularly in terms of meat consumption. Due to human’s susceptibility to this pathogen, detection methods and prevention measures should be implemented to reduce its incidence. Several pathogenic strains of C. perfringens have been identified so far. One of the potential concerns about this bacteri...